Chapter 2

Principles of Drug Action

  • Description of the basic chemistry of drugs and their relation to their properties

  • Define the hybridization, isomerism, chirality, stereochemistry, heteroatoms, and aromaticity, and their relation to the physicochemical properties of a drug

  • Define the solubility, protein interaction, and hydrogen bonding related to functional groups present in a drug structure

  • Define acid-base chemistry in relation to drug structure and properties like pKa

  • Define factors important to attain acidity or basicity

  • Importance of heteroatoms in a drug structure, especially nitrogen

  • Explain the drug action and importance of studying physicochemical properties

  • Understand how drug encounters the biological ...

Get Medicinal Chemistry, 2nd Edition now with O’Reilly online learning.

O’Reilly members experience live online training, plus books, videos, and digital content from 200+ publishers.