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Medicinal Chemistry, 2nd Edition
book

Medicinal Chemistry, 2nd Edition

by D. Sriram, P. Yogeeswari
May 2010
Intermediate to advanced
712 pages
18h 30m
English
Pearson India
Content preview from Medicinal Chemistry, 2nd Edition

Chapter 2

Principles of Drug Action

LEARNING OBJECTIVES
  • Description of the basic chemistry of drugs and their relation to their properties

  • Define the hybridization, isomerism, chirality, stereochemistry, heteroatoms, and aromaticity, and their relation to the physicochemical properties of a drug

  • Define the solubility, protein interaction, and hydrogen bonding related to functional groups present in a drug structure

  • Define acid-base chemistry in relation to drug structure and properties like pKa

  • Define factors important to attain acidity or basicity

  • Importance of heteroatoms in a drug structure, especially nitrogen

  • Explain the drug action and importance of studying physicochemical properties

  • Understand how drug encounters the biological ...

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Publisher Resources

ISBN: 9788131731444