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Medicinal Chemistry, 2nd Edition by P. Yogeeswari, D. Sriram

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Chapter 6

Local Anaesthetics

LEARNING OBJECTIVES
  • Compare general anaesthetics and local anaesthetics

  • List the ideal properties of a local anaesthetics

  • Explain the overall mechanisms of action of anaesthetics

  • Describe the clinical utility of local anaesthetics

  • Categorise the various modes of administration of local anaesthetics

  • Learn the discovery pathway of present-day local anaesthetics that originated from natural drug cocaine

  • List the various classes of local anaesthetics and their chemical structures

  • Describe the synthesis, uses, and doses of benzoic acid class of local anaesthetics

  • Describe the mechanism of action of benzocaine and how it is different from other anaesthetics

  • Describe the relationship between structure of benzoic acid ...

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