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Medicinal Chemistry, 2nd Edition by P. Yogeeswari, D. Sriram

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Chapter 9

Antipsychotic Agents

LEARNING OBJECTIVES
  • Define antipsychotics and their utility in various conditions

  • Categorize antipsychotics on the basis of the target at which they act

  • Describe the synthetic routes of each antipsychotics

  • Define the utility and doses of each antipsychotics

  • Describe the mechanism by which antipsychotics act, and their implications

  • Define the discovery and functional utility of phenothiazines

  • Discuss the structure-activity relationship on phenothiazines

  • Describe the neuroleptic SAR of butyrophenone

  • Define atypical antipsychotics and the need for design

  • Describe some newer drugs for psychosis treatment

9.1 INTRODUCTION

Antipsychotic drugs are used to treat psychosis, a severe mental illness in which people ...

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