May 2010
Intermediate to advanced
712 pages
18h 30m
English
Content preview from Medicinal Chemistry, 2nd Edition
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Chapter 18
Antihyperlipidemic Agents
LEARNING OBJECTIVES
Define hyperlipidemia and atherosclerosis, and their causes
Classify antihyperlipidemics based on the structure and mode of action
Define HMG-CoA and its role in hyperlipidemia
Define the pharmacophoric requirements of the statin class of antihyperlipidemics
Describe some antihyperlipidemics obtained from fermentation process
Describe the cholesterol biosynthetic pathway and its significance
Define PPAR?-inhibitors and their utility
Describe some new drug classes useful in the treatment of hyperlipidemia and atherosclerosis
18.1 INTRODUCTION
As a regulator of homeostasis, a precursor to the corticosteroids and sex hormones, and a critical factor in the maintenance of cell-wall integrity, ...
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I'm always learning. So when I got on to O'Reilly, I was like a kid in a candy store. There are playlists. There are answers. There's on-demand training. It's worth its weight in gold, in terms of what it allows me to do.