Chapter 26

Antibiotics

LEARNING OBJECTIVES
  • Define antibiotics and developmental pathway of various antibiotics

  • Define β-lactam antibiotics and their importance

  • Categorize penicillins and describe how penicillins are degraded

  • Discuss the structural importance of penicillins

  • Define cephalosporins and classify according to their generation

  • Describe the degradation pathway of cephalosporins

  • Discuss the structural modifications and their effect on biological activity of cephalosporins

  • Define tetracycline antibiotics and its utility

  • Describe the structural importance of tetracycline and its mode of action

  • Define macrolide antibiotics and its chemistry

  • Describe the chemistry and utility of aminoglycoside antibiotics

  • List some newer antibiotics ...

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