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Medicinal Chemistry, 2nd Edition
book

Medicinal Chemistry, 2nd Edition

by D. Sriram, P. Yogeeswari
May 2010
Intermediate to advanced
712 pages
18h 30m
English
Pearson India
Content preview from Medicinal Chemistry, 2nd Edition

Chapter 28

Antifungal Agents

LEARNING OBJECTIVES
  • Define fungal infections and the treatment options

  • Categorize antifungals

  • Describe the chemistry and utility of antifungal antibiotics

  • Describe the mode of action and structure of azole antifungals

  • Discuss the utility of pyrimidine antifungals

  • Discuss the other structural classes of antifungals

  • List some new drugs in the antifungal category

28.1 INTRODUCTION

Most fungal infections (mycoses) involve superficial invasion of the skin or mucous membrane of body orifices. These diseases, which can usually be controlled by local application of antifungal agents, are divided into two etiologic groups:

  1. The dermatophytes, which are contagious superficial epidermal infections caused by various
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Publisher Resources

ISBN: 9788131731444