May 2010
Intermediate to advanced
712 pages
18h 30m
English
Content preview from Medicinal Chemistry, 2nd Edition
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Chapter 29
Antiviral Agents
LEARNING OBJECTIVES
Define HIV and AIDS with a view on the HIV life cycle
Describe the potential drug targets in the HIV life cycle
Categorize anti-HIV drugs based on the stage of intervention in the replicative cycle
Discuss the classes of reverse transcriptase inhibitors and compare nucleoside and non-nucleoside inhibitors
Describe the mode of action of each class of anti-HIV drugs
Define protease inhibitors and their importance
Define anti-HSV drugs and their utility
List some miscellaneous classes of antivirals
Describe the newer antiviral drugs
In the past few years, the antiviral chemotherapy area has witnessed a remarkable turnover of antiviral compounds, particularly in the domain of nucleoside analogues. ...
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