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Medicinal Chemistry, 2nd Edition by P. Yogeeswari, D. Sriram

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Chapter 30

Antiprotozoal Agents

LEARNING OBJECTIVES
  • Define antiamoebic agents and their utility
  • Categorize amoebicides based on the mode of treatment
  • Define malaria and the treatment options
  • Classify antimalarials based on the chemical structure
  • Describe the life cycle of malaria and the targets for drug development
  • Define antihelmintics and their utility
  • Categorize antihelmintics
  • List other antiprotozoal drugs, their synthesis and utility
  • Describe newer drugs in the class of antiprotozoals
30.1 INTRODUCTION

Human beings are host to a wide variety of protozoal parasites, which can be transmitted by insect vector, directly from mammalian reservoirs, or from one person to another. Because protozoa multiply in their hosts and vaccination ...

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