May 2010
Intermediate to advanced
712 pages
18h 30m
English
Content preview from Medicinal Chemistry, 2nd Edition
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Chapter 32
Prostaglandins
LEARNING OBJECTIVES
Define prostaglandins and their important functions
Describe the biosynthetic pathway of various prostaglandins
Describe the naming pattern used for prostaglandins
Describe various synthetic methods available for prostaglandins
List out the therapeutically useful prostaglandins
Derive the relationship between structure and activity of prostaglandins
32.1 INTRODUCTION
Prostaglandins were first discovered and isolated from human semen in the 1930s by Ulf von Euler of Sweden. Thinking they had come from the prostate gland, he named them prostaglandins. It has since been determined that they exist and are synthesised in virtually every cell of the body. Prostaglandins are like hormones in that ...
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