May 2010
Intermediate to advanced
712 pages
18h 30m
English
Content preview from Medicinal Chemistry, 2nd Edition
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Chapter 33
Steroids
LEARNING OBJECTIVES
Define steroids and the biosynthetic pathway of steroidal hormones
Describe the mode of action of steroidal hormones
Define oestrogens and describe their functions
Describe the therapeutically useful oestrogens and progestins
Define androgens and their major functions
Describe the glucocorticoids and their mode of action
Describe the importance of structure and activity profile of all steroidal hormones
33.1 INTRODUCTION
Steroids are structurally related compounds that have a common cyclopentano perhydro phenanthrene nucleus. They are widely distributed in the plant and animal kingdom. The fused tetracyclic steroid nucleus provides the carbon framework for at least four large groups of mammalian ...
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