Cell Membrane Biology and Juxtacrine Signal Conversion
Mark L. Tykocinski, Department of Pathology, Anatomy and Cell Biology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA
Our contemporary view of the cell membrane pictures a highly dynamic structure endowed with a rich functional repertoire. This chapter describes the evolution of our understanding of membrane structure and function, and introduces the notion of ‘cell membrane emergence’ as a robust conceptual framework for bringing systems perspectives into this field. The notion of multi-tiered emergent states is of particular interest with respect to membrane proteins, in terms of their surface distribution, dynamic structure, and inbound and ...
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