Chapter 2

Cell Surface Engineering by Chemical Reaction and Remodeling

Wade M. Fox1 and Debanjan Sarkar1, 2,    1Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY, USA,    2Department of Biomedical Engineering, University at Buffalo, The State University of New York, Buffalo, NY, USA

Cell surface modification with covalent approaches provides novel bioengineering tools to conjugate functional molecules and structures on the cell surface. Immobilization of specific molecules and structures can precisely control the interactions of the cell with its extracellular microenvironment. Since cell membrane contains functional molecules with specific chemical signatures, covalent ...

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