Engineering the Surface of Cells Using Biotin–Avidin Chemistry
Kawther K. Ahmed, Sean M. Geary and Aliasger K. Salem, College of Pharmacy, University of Iowa, Iowa City, IA, USA
This chapter is dedicated to the use of biotin-avidin chemistry to functionalize cell surfaces for a range of biomedical and biotechnological applications. The importance of different avidin analogs and methods of cell surface biotinylation are discussed. The valuable role of biotin-avidin chemistry in augmenting tissue engineering is highlighted as well as its role in generating cell-particle hybrids for downstream medical purposes such as cancer vaccines and targeted drug delivery.
Keywords
Avidin; Biotin; streptavidin; Tissue engineering; Biotinylation; ...
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