References

  1. International Conference of Harmonisation. (1994). E4: Dose–Response Information to Support Drug Registration. Available at: http://www.ich.org/fileadmin/Public_Web_Site/ICH_Products/Guidelines/Efficacy/E4/Step4/E4_Guideline.pdf.
  2. Thomas N. (2006). Hypothesis testing and Bayesian estimation using a sigmoid Emax model applied to sparse dose-response designs. Journal of Biopharmaceutical Statistics 16: 657-677.
  3. Bretz F, Pinheiro JC & Branson M. (2005). Combining multiple comparisons and modeling techniques in dose-response studies. Biometrics 61: 738-748.
  4. MacDougall J. (2006). Analysis of dose-response studies-Emax model. In Ting N, ed. Dose Finding in Drug Development. New York: Springer.

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