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Modern Discoveries in Neuroscience... And What They Reveal About You (Collection) by Masao Ito, Dale Purves, Miriam Boleyn-Fitzgerald, Andrew Koob

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9. Network Models

9-1. Introduction

Having just considered the diverse cellular and molecular events occurring in the cerebellum, we can now examine how information is processed in its neuronal circuits. Since the monumental Marr and Albus contributions, various models have been proposed. In this chapter, we see how our understanding of such models has advanced recently.

9-2. Mossy Fiber-Granule Cell Relay

Mossy fibers, the major inputs to the cerebellar cortex, make synaptic connections with the most numerous small neurons in this cortex, the granule cells. These connections follow a characteristic asymmetric pattern of divergence and convergence; one mossy fiber branches to contact with 400–600 or more granule cells, whereas each granule cell ...

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