As I'm sure you already know, communication and feedback are absolutely vital to a successful outcome of any course. Moodle offers many different ways to communicate with your learners. A whole chapter is dedicated to communication tools, that's how important I feel communicating with your learner is. Start by browsing Chapter 8, and before you start setting up your course, add communicative strategies to your planning stage. Plan how you will communicate with your learners and how your learners can contact each other, work in groups, and have peer time using Moodle. The younger generations live in an online world anyway; they will take to it like fish to water.
Obviously, your communication strategies will differ depending on whether you have a course that's completely online or a course where you have face-to-face interaction with your learners. Even if you do have physical presence, using Moodle for detailed feedback for assignments and quizzes may save you and your learners time — they will come prepared or may even ask questions in chat or e-mail, saving face-to-face time for course work.