Chapter 7Bio-Sensing Performance of Magnetite Nanocomposite for Biomedical Applications
Rajasekhar Chokkareddy, Natesh Kumar Bhajanthri, Bakusele Kabane and Gan G. Redhi*
Electroanalytical Laboratories, Department of Chemistry, Durban University of Technology, Durban South Africa
*Corresponding author: redhigg@dut.ac.za
Abstract
Previously, the focus of interest in magnetic nanoparticles had a very significant part in biomedical applications and has been the topic of much interest in research groups. Physico-chemical properties of magnetic nanoparticles, i.e., nanoparticle size, surface chemistry, and, composition, vary widely with the impact of their biological and pharmacological properties, and finally, their medical usages. Furthermore, in cellular imaging and molecular application of various magnetic nanoparticles which include super paramagnetic iron oxide nanoparticles were initiated to nontoxic nature and used as contrast agents in magnetic resonance imaging. In addition, drug conveyance through hyperthermia, magnetic targeting, as well as labeling of stem cells have also remained as the source of travel and a prospective therapeutic choice. Recent advancement in the evolution and categorizing of active biomagnetic nano-materials, and their interactions with biological molecules, and their usage in bioanalytical sensors have been discussed in this chapter. Lastly, the surface coating of magnetic nanoparticle procedures is shortly described and various magnetic nanomaterials ...
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