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Nanostructures for Novel Therapy by Alexandru Mihai Grumezescu, Denisa Ficai

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Chapter 3

Functionalization of nanoparticles in specific targeting and mechanism release

Giorgia Adamo
Simona Campora
Giulio Ghersi    University of Palermo, Palermo, Italy

Abstract

The development of various nanotechnologies have provided a new field of research, which allows the manipulation of molecular components of matter and covers a vast array of nanodevices. The “smart” multifunctional nanostructures should work as customizable, targeted drug-delivery vehicles capable of carrying large doses of therapeutic agents into malignant cells. Some nanomedical approaches are based on the use of functionalized nanoparticles (NPs), not only to reduce toxicity and side effects of drugs but, also in potential the biological barriers crossing on, such ...

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