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Nanostructures for Novel Therapy by Alexandru Mihai Grumezescu, Denisa Ficai

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Chapter 8

Electrospinning and surface modification methods for functionalized cell scaffolds

Naruki Kurokawa
Fuyuaki Endo
Tomoki Maeda
Atsushi Hotta    Keio University, Yokohama, Japan

Abstract

For tissue engineering scaffolds, fibrous structures are effective due to morphology similar to that of extracellular matrix. Cell attachment and its proliferation could be enhanced by the structural optimization and the surface modification of the scaffolds. In this chapter, effective techniques for making optimal scaffolds, including electrospinning and surface modification methods, will be discussed. Electrospinning is a process whereby polymer nanofibers can be formed in an electrostatic field. The nanoscale diameter and the high porosity of the electrospun ...

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