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Nanostructures for Novel Therapy by Alexandru Mihai Grumezescu, Denisa Ficai

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Chapter 9

Short peptide self-assembled nanostructures for therapeutics innovative delivery

Daniel Iglesias
Silvia Marchesan    University of Trieste, Trieste, Italy

Abstract

Self-assembly of peptides into nanostructured materials and hydrogels is rising as an innovative approach for the delivery of therapeutics. In particular, short peptides are especially attractive due to their low-cost of preparation, ease of scale-up, and possibility to be accessed by different means, including liquid-phase synthesis, and biocatalysis. Their self-assembly into nanostructures can be used for drug delivery in many diverse and innovative ways, depending on the intended application and desired drug release profile. Drugs can be physically entrapped in hydrogels, ...

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