O'Reilly logo

Nanostructures for Novel Therapy by Alexandru Mihai Grumezescu, Denisa Ficai

Stay ahead with the world's most comprehensive technology and business learning platform.

With Safari, you learn the way you learn best. Get unlimited access to videos, live online training, learning paths, books, tutorials, and more.

Start Free Trial

No credit card required

Chapter 30

Role of Excipients in formulation development and biocompatibility of lipid nanoparticles (SLNs/NLCs)

Slavomira Doktorovova*
Ranjita Shegokar**
Eliana B. Souto**    University of Coimbra, Coimbra, Portugal**    Freie Universität Berlin, Berlin, Germany

Abstract

Lipid nanoparticles are widely explored in many therapeutic, targeting, and imaging areas. Among the various nanoplatforms, lipid-based nanostructures offer better attributes to drug delivery, such as high loading capacity, biocompatibility, improved physicochemical and long-term stability, ease of surface modification, adjustable drug release, and enhanced bioavailability. Despite the extensive number of publications focusing on the development of lipid nanoparticles, very limited ...

With Safari, you learn the way you learn best. Get unlimited access to videos, live online training, learning paths, books, interactive tutorials, and more.

Start Free Trial

No credit card required