Chapter 5

Functional Nucleic Acid-Directed Assembly of Nanomaterials and Their Applications as Colorimetric and Fluorescent Sensors for Trace Contaminants in Water

Debapriya Mazumdar1, Juewen Liu2 and Yi Lu3,    1ANDalyze, Inc. Chicago, IL, USA,    2University of Waterloo, Waterloo, ON, CA,    3Center of Advanced Materials for the Purification of Water with Systems, Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA

Largely due to the high extinction coefficients and distance-dependent optical properties, metallic nanoparticles and quantum dots have been shown to be very attractive in DNA-related colorimetric and fluorescent assays, respectively. We have used DNAzymes (DNA molecules with catalytic activities) ...

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