October 2012
Beginner to intermediate
582 pages
15h
English
Content preview from Open Source Software in Life Science Research
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8
GenomicTools: an open source platform for developing high-throughput analytics in genomics
Aristoteli.s. Tsirigos, Niin.a. Haiminen, Erha.n. Bilal and Filipp.o. Utro
Abstract:
Following the dramatic reduction of sequencing cost, research laboratories have been producing huge amounts of data, measuring DNA variations, RNA abundances, protein–DNA interactions, DNA methylation levels, and even chromosomal conformations. Making sense of terabytes of data requires reliable data management, computational resources, and, eventually, efficient computational methods for pre-processing, quality control, analysis and meta-analysis. In this work, we present a flexible computational platform for facilitating the development of pipelines to accomplish ...