Chapter 7Local Nucleic Acid Analysis of Adherent Cells
Aditya Kashyap, Deborah Huber, Julien Autebert and Govind V. Kaigala
IBM Research – Zurich, Säumerstrasse 4, 8803 Rüschlikon, Switzerland
7.1 Introduction
7.1.1 Heterogeneity in Cells and Their Microenvironments
Most physiological processes are consequences of cells interacting with their microenvironment to perform healthy tissue-level functions [1–4]. This microenvironment can be the surrounding extracellular matrix or different cell types constituting a tissue. Interactions within the microenvironment predominantly comprise direct physical contact [4–6], migration [7], and multimodal signal transduction [8]. Understanding and elaborating the causes and effects of such interactions ...
Get Open-Space Microfluidics now with the O’Reilly learning platform.
O’Reilly members experience books, live events, courses curated by job role, and more from O’Reilly and nearly 200 top publishers.
