Chapter 8Microfluidic Probe for Neural Organotypic Brain Tissue and Cell Perfusion
Donald MacNearney, Mohammad A. Qasaimeh and David Juncker
McGill University and Genome Québec Innovation Centre, Biomedical Engineering Department, 740 Dr. Penfield Ave. #6206, Montreal, QC, H3A 0G1, Canada
8.1 Introduction
Developing a more detailed understanding of the structure and function of the brain is a cornerstone of modern neuroscience. To aid in this endeavor, organotypic brain slices have been used as model systems by neuroscientists for many years. Brain slices from many regions of the brain will, if prepared correctly, broadly retain the architecture and local synaptic function found in vivo [1]. Organotypic slices thus offer a window into brain ...
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