Skip to Main Content
Pharmaceutical Analysis
book

Pharmaceutical Analysis

by P. D. Chaithanya Sudha
July 2012
Intermediate to advanced content levelIntermediate to advanced
758 pages
17h 12m
English
Pearson India
Content preview from Pharmaceutical Analysis

Chapter 2

Molecular Weight Determinations

INTRODUCTION

Molecular weight of the compounds is determined by the determination of colligative properties. The methods are as follows:

  • Ebullioscopic method
  • Cryoscopic method
  • Vapour pressure lowering method
  • Mass spectrometric method
  • Osmometric method

In 1919, Cottrell vapour lift pump made it possible to measure the boiling point which proved useful for the measurement of the molecular weight.

Ebullioscopy

This method is commonly known as the boiling point elevation method. The boiling point is defined as the temperature at which the vapour pressure is equal to the atmospheric pressure. The boiling point depends on the solute dissolved in the solvent. It decreases when a non-volatile solute is present ...

Become an O’Reilly member and get unlimited access to this title plus top books and audiobooks from O’Reilly and nearly 200 top publishers, thousands of courses curated by job role, 150+ live events each month,
and much more.
Start your free trial

You might also like

An Introduction to Pharmaceutical Sciences

An Introduction to Pharmaceutical Sciences

J. Roy
Medicinal Chemistry, 2nd Edition

Medicinal Chemistry, 2nd Edition

D. Sriram, P. Yogeeswari
Engineering Chemistry

Engineering Chemistry

K. Sesha Maheswaramma

Publisher Resources

ISBN: 9789332515659