Skip to Main Content
Pharmaceutical Analysis
book

Pharmaceutical Analysis

by P. D. Chaithanya Sudha
July 2012
Intermediate to advanced content levelIntermediate to advanced
758 pages
17h 12m
English
Pearson India
Content preview from Pharmaceutical Analysis

Chapter 5

Particle Size Analysis

INTRODUCTION

Particle size is the physical property of the compound which influences the stability, solubility and processability. The unit for the particle size is micrometer (μm). There are different methods for the determination of the particle size, as follows:

  • Microscopy
  • Sieving method
  • Sedimentation method
  • Sensing zone method
  • Light scattering method
  • Surface area measurement method

The selection of the method is mainly based upon the following:

  • Nature of the compound
  • Solubility
  • Toxicity
  • Flowability
  • Cost
  • Specifcation requirements, etc.

Types of Diameters

  • Martin's diameter: This is the length of the line which bisects the particle.
  • Feret's diameter: this is the distance between the two tangents of the particle. ...
Become an O’Reilly member and get unlimited access to this title plus top books and audiobooks from O’Reilly and nearly 200 top publishers, thousands of courses curated by job role, 150+ live events each month,
and much more.
Start your free trial

You might also like

An Introduction to Pharmaceutical Sciences

An Introduction to Pharmaceutical Sciences

J. Roy
Medicinal Chemistry, 2nd Edition

Medicinal Chemistry, 2nd Edition

D. Sriram, P. Yogeeswari
Engineering Chemistry

Engineering Chemistry

K. Sesha Maheswaramma

Publisher Resources

ISBN: 9789332515659