Pharmaceutical Analysis

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Chapter 1 Radiometric Analysis

INTRODUCTION

George de Von Hevesy is the first person to use the radioactive compounds to determine the biological compounds. A radiotracer is defined as the chemical compound which contains the radioactive nuclei as an anion or a cation. The radioactivity is the emission of rays such as α, β and γ-rays. The examples of radionuclide are ³H and ¹⁴C which are frequently used for the analysis of the compounds:

Radium Radon ²²⁶

Radon ²²² + He⁺(α-particles)

Carbon¹⁴

Nitrogen⁷ + e⁻(β-particles)

Neon²⁰ Neon²⁰ +

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