14.8. Project Prioritization
An important set of decisions with which a pharmaceutical sponsor is faced is that of the choice of drug development projects and more generally of the prioritization of the projects chosen. This topic has been considered by a number of authors, in particular by Bergman and Gittins (1985) but also by Senn (1996, 1997, 1998), Senn and Rosati (2002), Zipfel (2003), and Burman and Senn (2003).
It is instructive to consider the simpler problem of deciding which drugs to develop, since assessing the value of potential projects prior to inclusion in a portfolio may also suggest how, if at all, those projects that are included might be prioritised. A simple analogy, which is frequently made, is that of packing a number ...
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