Pharmaceutical Statistics Using SAS
by Ph. D. Alex Dmitrienko, Ph. D. Christy Chuang-Stein, Sr. Ralph B. D'Agostino
6.3. The One-Way Layout
The one-way layout is a commonly used experimental design in biological research. A recent Web search of the archival scientific literature (Science Direct) covering the domain of published pharmacological, toxicological and pharmaceutical science research from 2000 to first quarter 2005 produced 3,671 hits pertaining to the application of a one-way layout as the means to address a specific scientific hypothesis. The one-way layout is a powerful means to study basic scientific questions because of its simplicity. Recall that in a one-way layout, experimental units (e.g., subjects) are randomly assigned to two or more treatment groups. The treatment groups could consist of two or more distinct treatments or increasing ...
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