III—BUCCAL DRUG DELIVERY SYSTEM
INTRODUCTION
Learning Objectives
- Introduction to drug absorption in the oral cavity
- Advantages and limitations of buccal drug delivery system
- Anatomy and pathways of drug absorption through oral mucosa
The oral route is the most popular route of drug administration. The duration of action of drug after oral administration is mainly a function of drug-related properties such as the rate of absorption and clearance as well as the residence time of the delivery system at the absorption site. Drug absorption site in the oral cavity may be either sublingual (under the tongue) or buccal (between the cheek and gingiva). Rapid absorption from these routes is observed because of the thin mucous membrane and rich blood ...
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