May 2017
Intermediate to advanced
340 pages
8h 16m
English
Content preview from PHP 7 Data Structures and Algorithms
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DNA sequencing using dynamic programming
We have just seen how to find the longest common subsequence. Using the same principle, we can implement DNA or protein sequencing, which can be very helpful for us in solving bioinformatic problems. For alignment purpose, we will use the most popular algorithm known as the Needleman-Wunsch algorithm. It is similar to our LCS algorithm, but the scoring system is different. Here, we score a match, mismatch, and gap in a different scoring system. There are two parts of the algorithm: one to calculate the matrix with possible sequence and the second part is tracking back the actual sequence with the best possible one. The Needleman-Wunsch algorithm provides the best global alignment solution for any given ...
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