Chapter 2

Methods of Fabrication

2.1 Patterning Techniques

The techniques of the formation of micro- and nano-patterns on surfaces with regard to chemical and biological substances is essential in sensor technology. These techniques have been summarized in a review by Hook, Voelcker, and Thissen (1). More detailed references can be found in this particular review. An overview of patterning techniques is given in Table 2.1.

Table 2.1 Patterning techniques (1)

Method Advantage Disadvantage
Contact and noncontact printing Quick and simple pattern formation Poor resolution, pattern dimensions limited
Electron beam lithography Highly resolved patterning, no need for a mask Slow processing time, clean environment required, expensive
Dip pen nanolithography Highly resolved patterning, high energy particle beams not required. Slow processing time
Photolithography Highly resolved patterning, large surface areas Rigorous experimental protocols.
Templating Low cost, quick and highly resolved inert environment, dimensions and geometries restricted
Imprint lithography Low cost, high resolution Limited number of molecules and substrates
Microcontact printing Simple method Limited number of molecules and substrates
Microfluidics Experimentally simple  
Micromoulding Experimentally simple Limited pattern geometries
Magnetic force based patterning Directly patterns cells and biomolecules Conducted in an inert environment

2.2 Coating Techniques

A comparative study using ...

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