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Progenitor and Stem Cell Technologies and Therapies by A Atala

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11

Adipose tissue-derived stem cell biology and therapy

R. Madonna and R. Decaterina,     ‘G. d’Annunzio’ University Italy

Abstract:

Coronary (CAD) and peripheral (PAD) artery diseases are major causes of morbidity and mortality, and millions of CAD and PAD patients are treated by various medications, bypass surgery or angioplasty around the world. These patients could benefit from therapies that would accelerate natural processes of postnatal collateral vessel formation, an approach referred to as therapeutic angiogenesis. The adipose tissue stromal cells (ADSCs) derived from the visceral and subcutaneous human adipose tissue have been recently shown to participate in blood vessel formation by paracrine activities and differentiation into ...

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