Genitourinary progenitor and stem cell biology and therapy
A. Atala, Wake Forest Institute for Regenerative Medicine, USA
Abstract:
Congenital abnormalities, trauma, infection, and cancer can all necessitate reconstructive surgery in the genitourinary tract. Currently, such surgeries may be performed with native non-urologic tissues, homologous tissues from a donor, heterologous tissues or substances, or artificial materials. However, these materials often lead to complications after reconstruction, including rejection of the implanted tissue, urinary stone formation, and even eventual malignancy. The fields of stem and progenitor cell biology combined with novel tissue engineering methods may soon allow replacement of lost or deficient ...
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