Chapter Six. Squandering R & D Resources

 

It isn’t that they can’t see the solution. It’s that they can’t see the problem.

 
 --G.K. Chesterton

The system through which medicines make it to the market in the Unites States has gone terribly awry. It’s not just that the big successes of the 1980s and 1990s in developing blockbuster drugs are not sustainable, as the drought in new drugs approved by the FDA reveals. It’s not just that the “low-hanging fruit has been picked” or that the easy drugs have already been developed. No, the problem is much more serious.

The system certainly does not lack resources. Collectively, drug firms spend tens of billions of dollars each year on research. The National Science Foundation estimated spending at $31 billion ...

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