Safety is the most important factor in any production. As such, it should be the top priority for the stage manager to know all safety procedures for the space, and the location of all first aid kits, fire extinguishers, emergency exits, and AED equipment (if applicable). It is also important to know the emergency protocol and safety locations of the venue. Remember, in this day and age, all decisions will eventually have to stand up to scrutiny and possible legal repercussions after the event is all said and done.
Note where all first aid kits are located; find out who is responsible for their upkeep and supply level (it might be the stage manager) and be sure they stay up to date in case of an emergency.