7Screening Constrained Formulation Systems
“Our objective is to reduce the number of ‘essential’ components that we have to work with … by finding those components that have no effects and/or equal effects …. .”
Ronald D. Snee and Donald W. Marquardt (1976)
Overview
The central theme of this book is the need to have a strategy for your formulations development work. Briefly stated, our proposed strategy, which has been successfully applied and refined for decades, is to first run screening experiments. These are to be followed by optimization experiments in order to better understand the effects of the critical components that were identified in the screening experiments. In this chapter we discuss screening experiments for formulations development ...
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