Chapter 4: Target identification and validation

Stephanie Kay Ashendena; Natalie Kurbatovab; Aleksandra Bartosikc    a Data Sciences and Quantitative Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge, United Kingdomb Data Infrastructure and Tools, Data Science and Artificial Intelligence, R&D, AstraZeneca, Cambridge, United Kingdomc Clinical Data and Insights, Biopharmaceuticals R&D, AstraZeneca, Warsaw, Poland

Abstract

Target identification and target validation are involved with the identification and validation of a target that can be modulated for a therapeutic purpose. Whilst there is much variation on what a target is and how to define one, we can consider a therapeutic target to be one that is involved with the mechanisms ...

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