Chapter 8: Precision medicine
Sumit Deswala; Krishna C. Bulusub; Paul-Michael Agapowc; Faisal M. Khand a Genome Engineering, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Swedenb Bioinformatics and Data Science, Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, United Kingdomc Oncology R&D Real World Evidence, AstraZeneca, Cambridge, United Kingdomd AI and Analytics, Data Science and Artificial Intelligence, Biopharma R&D, AstraZeneca, Gaithersburg, MD, United States
Abstract
It has been shown that several diseases have genetic basis and bias. These changes such as mutations, copy number alteration, epigenetic changes, and RNA expression cause disease progression, adverse events, and drug resistance, ...
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