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Plasticity and Reorganization in Neural Injury and Neural Grafting

Elizabeth M. Jansen

Walter C. Low

University of Minnesota Medical School

BRAIN DEVELOPMENT AND PLASTICITY

Brain development is a highly orchestrated process involving the formation and competitive elimination of connections between nerve cells. The intricacies of this process during normal development are clearly outlined by Huttenlocher (this volume). The establishment of appropriate connections is exquisitely vulnerable during critical periods of development. Traumatic insults during these periods can lead to permanent and devastating consequences and are clearly threats to optimal development. Yet, even in the face of apparently massive lesions, the nervous system ...

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