How to Capture Videos of Brains in Real Time — The scientists first engineered the animals’ neurons to fluoresce (glow), using a method called optogenetics. The stronger the neural signal, the brighter the cells shine. To capture this activity, they used a technique known as “light-field microscopy,” in which an array of lenses generates views from a variety of perspectives. These images are then combined to create a three-dimensional rendering, using a new algorithm called “seeded iterative demixing” (SID) developed by the team.
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