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Acknowledgments
Successful completion of a large project like this is possible only in the context of an understanding
family, engaging colleagues, and a supportive community. First and foremost, we thank our chil-
dren, Mark, Ben, and Julie, for relinquishing our time for many long hours while we worked on this
book. We thank our parents, Robert and Marilyn, and Lester and Judy, for all that they have done to
support the busy schedules of our children and ourselves. We thank our colleagues Jeremy Buhler
for guidance on the case study on biosequence comparison, Chris Gill for helpful discussions about
design patterns, Patrick Crowley and Fred ...