An Introduction to Pharmaceutical Sciences

6

Formulated drugs 2

Learning objective

In this chapter there is a discussion of a couple of advanced routes of administration. The parenteral route of administration and the pulmonary route of administration seem simple but are very delicate, and very good current good manufacturing practice (cGMP), quality control (QC), and quality assurance (QA) are required. Parenteral routes require the dosage forms to be sterile; aerosol dosage forms do not need to be sterile unless in aqueous-based inhalers. This chapter will show how water for injection (WFI) is made and kept sterile during storage. Other subjects covered in this chapter are lyophilization, an important technology for biotechnology based drugs; aerosol dosage forms; and metered dose ...