Chapter 17

Transforming Clinical Trials with Artificial Intelligence

Stefanie Lip

University of Glasgow

Shyam Visweswaran

University of Pittsburgh

Sandosh Padmanabhan

University of Glasgow

CONTENTS

17.1   Introduction

17.2   Patient Recruitment for Clinical Trials

17.3   Patient Selection for Clinical Trials

17.4   Synthetic Data in Clinical Trials

17.5   Trials for Precision Medicine

17.6   Conclusion

References

17.1   Introduction

Current treatment guidelines are implicitly based on an “average patient” which ignores the complexity of human pathophysiology that manifests with significant inter-individual differences in treatment response. (Mulder et al., 2018) Randomized controlled trials (RCTs) have been utilized for many years and are often ...

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