2.1 Introduction2.2 Molecular biology of SARS-CoV-22.3 Genomic and technology2.3.1 Next-generation sequencing (NGS)2.3.2 Genome sequencing of SARS-CoV-22.4 Genomic epidemiology of SARS-CoV-2 in Africa2.4.1 Introduction sources of SARS-CoV-22.4.2 Analysis of the spike (S) glycoprotein of SARS-CoV-22.5 Conclusion