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Computer-Aided Vaccine Design by S. Ranganathan, J Tong

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List of figures

1.1. Schematic of MHC class I structure. (a) Front view of a class I molecule in complex with antigenic peptide based on X-ray crystallographic structure. (b) Side view of the same molecule clearly showing the anatomy of the peptide-binding cleft formed by α-helices sitting on a platform of a β-sheet 4

1.2. Schematic of MHC class II structure. (a) Front view of a MHC class II molecule in complex with antigenic peptide extending out of the binding cleft based on X-ray crystallographic structure. (b) Side view of the same molecule showing the anatomy of the peptide-binding cleft formed by α-helices sitting on a platform of a β-sheet

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2.1. Schematic of an immunoglobulin molecule based on X-ray crystallographic structure ...

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