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Fluorescent Nanodiamonds

Book Description

The most comprehensive reference on fluorescent nanodiamond physical and chemical properties and contemporary applications

Fluorescent nanodiamonds (FNDs) have drawn a great deal of attention over the past several years, and their applications and development potential are proving to be manifold and vast. The first and only book of its kind, Fluorescent Nanodiamonds is a comprehensive guide to the basic science and technical information needed to fully understand the fundamentals of FNDs and their potential applications across an array of domains. In demonstrating the importance of FNDs in biological applications, the authors bring together all relevant chemistry, physics, materials science and biology.

Nanodiamonds are produced by powerful cataclysmic events such as explosions, volcanic eruptions and meteorite impacts. They also can be created in the lab by high-pressure high-temperature treatment of graphite or detonating an explosive in a reactor vessel. A single imperfection can give a nanodiamond a specific, isolated color center which allows it to function as a single, trapped atom. Much smaller than the thickness of a human hair, a nanodiamond can have a huge surface area that allows it to bond with a variety of other materials. Because of their non-toxicity, nanodiamonds may be useful in biomedical applications, such as drug delivery and gene therapy. 

  • The most comprehensive reference on a topic of rapidly increasing interest among academic and industrial researchers across an array of fields
  • Includes numerous case studies and practical examples from many areas of research and industrial applications, as well as fascinating and instructive historical perspectives
  • Each chapter addresses, in-depth, a single integral topic including the fundamental properties, synthesis, mechanisms and functionalisation of FNDs
  • The first book published by the key patent holder with his research group in the field of FNDs

Fluorescent Nanodiamonds is an important working resource for a broad range of scientists and engineers in industry and academia. It will also be a welcome reference for instructors in chemistry, physics, materials science, biology and related fields.

Table of Contents

  1. Cover
  2. Preface
  3. Part I: Basics
    1. 1 Introduction to Nanotechnology
      1. 1.1 Nanotechnology: From Large to Small
      2. 1.2 Nanocarbons: Now and Then
      3. References
    2. 2 Nanodiamonds
      1. 2.1 Ah, Diamonds, Eternal Beautiful
      2. 2.2 Diamonds: From Structure to Classification
      3. 2.3 Diamond Synthesis
      4. 2.4 Nanodiamonds: A Scientist’s Best Friend
      5. References
    3. 3 Color Centers in Diamond
      1. 3.1 Nitrogen Impurities
      2. 3.2 Crystal Defects
      3. 3.3 Vacancy‐Related Color Centers
      4. 3.4 The NV Center
      5. References
    4. 4 Surface Chemistry of Nanodiamonds
      1. 4.1 Functionalization
      2. 4.2 Bioconjugation
      3. 4.3 Encapsulation
      4. References
    5. 5 Biocompatibility of Nanodiamonds
      1. 5.1 Biocompatibility Testing
      2. 5.2 In Vitro Studies
      3. 5.3 Ex Vivo Studies
      4. 5.4 In Vivo Studies
      5. References
    6. 6 Producing Fluorescent Nanodiamonds
      1. 6.1 Production
      2. 6.2 Characterization
      3. References
  4. Part II: Specific Topics
    1. 7 Single Particle Detection and Tracking
      1. 7.1 Single Particle Detection
      2. 7.2 Single Particle Tracking
      3. References
    2. 8 Cell Labeling and Fluorescence Imaging
      1. 8.1 Cell Labeling
      2. 8.2 Fluorescence Imaging
      3. References
    3. 9 Cell Tracking and Deep Tissue Imaging
      1. 9.1 Cellular Uptake
      2. 9.2 Cell Tracking
      3. 9.3 Deep Tissue Imaging
      4. References
    4. 10 Nanoscopic Imaging
      1. 10.1 Diffraction Barrier
      2. 10.2 Superresolution Fluorescence Imaging
      3. 10.3 Cathodoluminescence Imaging
      4. 10.4 Correlative Light‐Electron Microscopy
      5. References
    5. 11 Nanoscale Quantum Sensing
      1. 11.1 The Spin Hamiltonian
      2. 11.2 Temperature Sensing
      3. 11.3 Magnetic Sensing
      4. References
    6. 12 Hybrid Fluorescent Nanodiamonds
      1. 12.1 Silica/Diamond Nanohybrids
      2. 12.2 Gold/Diamond Nanohybrids
      3. 12.3 Silver/Diamond Nanohybrids
      4. 12.4 Iron Oxide/Diamond Nanohybrids
      5. References
    7. 13 Nanodiamond‐Enabled Medicine
      1. 13.1 NDs as Therapeutic Carriers
      2. 13.2 Drug Delivery
      3. 13.3 Gene Therapy
      4. 13.4 Animal Experiments
      5. References
    8. 14 Diamonds in the Sky
      1. 14.1 Unidentified Infrared Emission
      2. 14.2 Extended Red Emission
      3. 14.3 Cosmic Events at Home on Earth
      4. References
  5. Further Reading
    1. Review Articles
    2. General References
  6. Index
  7. End User License Agreement