High Performance Deformable Image Registration Algorithms for Manycore Processors

Chapter 3

Multimodal B-Spline Registration

Information in This Chapter

• Overview of Multimodal B-Spline Registration

• Mutual Information as A Cost Function

• Efficient Computation of Mutual Information

• Gradient Descent Optimization to Iteratively Tune the B-Spline Coefficients

• Performance Evaluation

3.1 Introduction

The B-spline deformable registration algorithm maps each and every voxel in a fixed or static image S to a corresponding voxel in a moving image M as described by a deformation field , which is defined at each and every voxel within the static image. An optimal deformation field accurately describes how the voxels in M have ...