Real World Health Care Data Analysis

Chapter 15: Personalized Medicine, Machine Learning, and Real World Data

15.1 Introduction

15.2 Individualized Treatment Recommendation

15.2.1 The Individualized Treatment Recommendation Framework

15.2.2 Estimating the Optimal Individualized Treatment Rule

15.2.3 Multi-Category ITR

15.3 Programs for ITR

15.4 Example Using the Simulated REFLECTIONS Data

15.5 “Most Like Me” Displays: A Graphical Approach

15.5.1 Most Like Me Computations

15.5.2 Background Information: LTD Distributions from the PCI15K Local Control Analysis

15.5.3 Most Like Me Example Using the PCI15K Data Set

15.5.4 Extensions and Interpretations of Most Like Me Displays

15.6 Summary

References

15.1 Introduction

Chapters 6–9 in this text demonstrated methods for estimating the ...